9th Symposium of the NRS platform experimental models in pulmonary research

On October 11th, 2019, the NRS platform experimental models in pulmonary research organizes the 9th symposium in Utrecht, Nutricia Research, Uppsalalaan 12, 3584 CT Utrecht, de Uithof.

Our aim is to optimize the use of experimental models in lung research and to stimulate and facilitate collaborations between research groups of the academia and industry. During this 9th symposium, experts in the field, post-docs and PhD students will give an overview of the models used in pulmonary research such as asthma, neonatal lung disease, pulmonary infection and drug development.

Our keynote speakers, professor dr. Philip Hansbro (Centre for Inflammation, University of Technology, School of Life Sciences, Ultimo, NSW 2007 & Centenary Institute, Sydney, NSW 2209, and Priority Research Centre for Healthy Lungs, University of Newcastle, & Vaccines, Infection, Viruses & Asthma (VIVA) group, Hunter Medical Research Institute, Newcastle, Australia) and professor dr. David Schwartz (Professor of Medicine and Immunology, Department of Medicine, University of  Colorado, Denver, USA) will present on animal models for Asthma COPD, lung cancer and IPF to develop improved therapy.

We invite all NRS members that are (interested in) working with experimental models in pulmonary disease.

Program

Download the full program here.

9.45-10.15 hr. Coffee/Tea, welcome and introduction.
Gert Folkerts (Pharmacology, Utrecht University), Rudi Hendriks (Pulmonology, Erasmus MC, Rotterdam) and Gerry Wagenaar (Faculty of Science, Free University, Amsterdam).

10.15-12.00 hr. Asthma and COPD

*         (10.15-11.00 hr. Keynote lecture - Use of mouse models of severe asthma and COPD to develop                                       improved therapies.
           Philip Hansbro, Director, Centre for Inflammation, University of Technology, School of Life Sciences, Ultimo, NSW 2007             & Centenary Institute, Sydney, NSW 2209. Priority Research Centre for Healthy Lungs, University of Newcastle,                         Vaccines, Infection, Viruses & Asthma (VIVA) group, Hunter Medical Research Institute, Newcastle, Australia.   
*          Notch signaling licenses allergic airway inflammation in mice by promoting lymph node egress of T helper 2 cells. 
            Rudi Hendriks, Department of Pulmonary Medicine, Erasmus MC Rotterdam
*          Optimization of an in vitro bronchial epithelial cell model for chronic air pollution exposure.           
           Hamed Janbazacyabar, Department of Pharmacology, UIPS, Utrecht University.

12.00-12.45 hr. Lunch

12.45-13.45 hr. Airway barrier function and disease modelling in organoids
*          Short-chain fatty acids increase and restore the barrier function of human bronchial airway epithelial cells. 
            Levi B. Richards, Department of Respiratory Medicine, Amsterdam UMC, location AMC
*          Disease modelling in organoids for pharmacological research.
           Xinhui Wu, Department of Molecular Pharmacology, University of Groningen, Groningen.

13.45-14.45 hr. Airway inflammation and respiratory infections
*          Mechanism behind the Anti-inflammatory action of oligosaccharides in vitro and in vivo: respiratory infections studies.
            Yang Cai, Department of Pharmacology, UIPS, Utrecht University.
*          Pathogenesis of Varicella Pneumonia.
           Georges Verjans, Department of Virosciences, Erasmus MC Rotterdam.

14.45-15.15 hr. Coffee and tea break

15.15-16.15 hr. Neonatal and pediatric lung disease
*          Elucidating the impact of combined hyperoxia and antibiotics exposure on lung mesenchymal stromal cell populations               and lung development in neonatal mice.
           Jennifer Collins, Department  Pediatric Surgery, Sophia Children's Hospital, Erasmus University Medical                                     Centre, Rotterdam.
*         
Perinatal stress and adverse pulmonary outcomes – lessons from pre-clinical ovine models.
            Helene Widowski, Department of Pediatrics, Maastricht University Medical Center, Maastricht.

16.15-17.00 hr. Keynote lecture - Idiopathic Pulmonary Fibrosis: a genetic disease involving the peripheral airways.
            David Schwartz, Professor of Medicine and Immunology, Department of Medicine, University of Colorado, Denver,                      USA.

17.00-18.30 hr. Network meeting, Drinks and Italian Buffet, “Nutricia Tour” guided by Karin Knipping (25 min)

The closure of the symposium includes a tour at Nutricia Research and an informal dinner (Italian buffet) for which you are invited as well. Please indicate in the registration if you stay for dinner at the end of the symposium.

 

NRS membership is mandatory. After that the attendance is free of charge!

PLEASE BRING YOUR PASSPORT OR DRIVER'S LICENCE IN ORDER TO ENTER THE BUILDING WHERE THE WHOLE MEETING WILL TAKE PLACE.

Best wishes from the NRS platform experimental models,

Gerry T.M. Wagenaar (g.t.m.wagenaar@vu.nl), Gert Folkerts (G.Folkerts@uu.nl), Rudi Hendriks (r.hendriks@erasmusmc.nl).

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