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10th Symposium of the NRS platform Experimental Models in pulmonary research

Symposium of the NRS platform experimental models in pulmonary research

When: October 29th, 2021.

Location: David de Wied gebouw, M2.01, Universiteitsweg 99, 3584 CG Utrecht, de Uithof.

9.45-10.15 hr. Coffee/Tea, welcome and introduction.
Gert Folkerts (Pharmacology, Utrecht University), Rudi Hendriks (Pulmonology, Erasmus MC, Rotterdam) and Gerry Wagenaar (Faculty of Science, VU University, Amsterdam).

10.15-11.00 hr. Keynote lecture.
*          Novel imaging of airway remodeling in bronchial thermoplasty-treated asthma patients.
            Johannes de Boer. Department of Physics, VU University Amsterdam.

11.00-12.30 hr. Asthma and airway infection.
*          In vitro analyses of human ILC2 cells in asthma.
            Esmee van der Ploeg. Department of Pulmonary Medicine, ErasmusMC Rotterdam.
*          hPSC-derived airway cholinergic neurons on chips for disease modelling of airway neuroplasticity in asthma.
            Pien Goldsteen. Department of Molecular Pharmacology, University of Groningen.
*          Blunted inflammatory response to respiratory syncytial virus in lung epithelial cells from patients with astma.
           Aurore Gay. Department of Pathology and Medical Biology, UMC Groningen.

12.30-13.15 hr. Lunch.

13.15-14.45 hr. Animal models for intratracheal administration, ageing, lung cancer and cachexia.
*          Effective, reproducible and accurate intratracheal administration of solutions in mice.
            Charlotte Pelgrim. Utrecht Institute for Pharmaceutical Sciences, Division of Pharmacology, Utrecht University.
Accelerated aging in ERCC1/delta7 mice.
            Alex Kleinjan. Department of Pulmonary Medicine, ErasmusMC Rotterdam.
*          Lung cancer cachexia.
            Ramon Langen. Department of Respiratory Medicine, NUTRIM, Maastricht University.

14.45-15.15 hr. Coffee and tea break.

15.15-16.15 hr. Lung-gut axis in respiratory infection and COPD.
*          Oligosaccharides to suppress respiratory infections: A translational approach.
            Yang Cai. Department of Pharmacology Utrecht University, Wageningen University and Research, and ErasmusMC

*          Changes in intestinal homeostasis and immunity in a cigarette smoke- and LPS-induced murine model of COPD: the
            lung-gut axis.
*           Lei Wang. Department of Pharmacology, Utrecht University and Department of Respiratory Medicine, Maastricht

16.15-17.00 hr. Keynote lecture.
*          Targeting the endothelium to treat pulmonary disease.
           Jurjan Aman. Department of Pulmonary Medicine, Amsterdam UMC, location VUMC.

17.00-18.30 hr. Network meeting, drinks and Italian buffet.