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NRS 11th Young Investigators Symposium November 15th 2019 "Treatable traits"

Hotel Casa 400, Eerste Ringdijkstraat 4
1097 BC Amsterdam, Amsterdam (near train station Amsterdam, Amstel).
We advise you to travel by train due to limited parking possibilities. 

Powered by Stichting Astma Bestrijding (SAB)

Registration closed

The YIS is organized specifically for young investigators (PhD students, post-docs) and young physicians in training doing research within the field of lung diseases in the Netherlands. This symposium gives the opportunity to start/broaden your network in the Netherlands, to practice presenting and to discuss data, and of course to be inspired by the seminars given by (inter)national Keynote speakers from the ‘Lung Field”. Obviously, starting PIs that are interested in the symposium are more than welcome to join this day. 

The NRS and it's activities are sponsored by:


08:45-09:15     Arrival and registration        
09:15-09:20     Welcome (Room: UvA 4)
09:20-10:40     Session I
Prof. dr. Alvar Agustí, Respiratory Institute, Hospital Clinic, University of Barcelona, Spain
“COPD: a changing paradigm”                       

Prof. dr. Leo Koenderman, University Medical Centre Utrecht, the Netherlands
“Treatable traits in chronic pulmonary diseases: the impact of heterogeneity and plasticity of the immune response”

10:40-11:00     Coffee  

11:00-12:00     Session II
Prof. dr. Michel van den Heuvel, Radboud University Medical Centre in Nijmegen, The Netherlands
“Treatable traits in pulmonary oncology”

Prof. dr. Job van der Palen, Medisch Spectrum Twente and University of Twente, Enschede, the Netherlands
“Self-management and behavior change in respiratory diseases”

12:00-12:30     Prof. dr. Alvar Agusti, Prof. dr. Leo Koenderman, Prof. dr. Michel van den Heuvel, Prof. dr. Job van der Palen 
Panel discussion Treatable traits; hype or hope”

12:30-13:20     Lunch

13:20-13:30     Dr. Marieke Duiverman, UMC Groningen
Discussion on mentor program

13:30-14:00     Anne Leendertse and Dr. Susanne Vijverberg, UMC Amsterdam
Patient interview - Patient participation in research                                                                                                                   

14:00-16:30     Masterclasses                                                                                
Prof. dr. Leo Koenderman (cell biology of inflammation)  - Room Stellenbosch
Prof. dr. Michel van den Heuvel (biomarkers in oncology) - Room Harvard          
Prof. dr.
Job van der Palen (behavior and self-care) - Room Heidelberg

14:00-16:30     Dr. Sara Maria Sprinkhuizen - Room UvA 4
Workshop “Data visualisation for researchers                           

16:30-17:00     Awards and closing
Chiesi presentation award
Master class Award
SAB award

View poster YIS 2019


The masterclasses are for junior researchers (e.g. PhD students) and will allow you to present your research to a small group of peers and receive feedback from one of the expert. With submission you can choose your expert. A tip from the organizing committee: do not choose your own supervisor! This is the opportunity to receive feedback from an (other) expert, even if his/her expert field is not totally overlapping the subject of your own research, he/she will give valuable feedback from another point of view. 

Please submit your abstract (maximum 300 words, 1 figure) before November 1st 2019. If you do not have any results from your study yet, just make an abstract covering the background, hypothesis and methods of your study. Preliminary data are also acceptable. All abstracts will be accepted, so you will not receive a confirmation. Upon arrival and registration on November 15th, you will receive an overview of participants of each masterclass. 

The presentation will be projected on a TV screen during the Masterclass and each participant has 5 minutes to explain his/her study, followed by a short discussion (5-10 minutes). Your presentation should be prepared in PowerPoint in landscape format. The presentation should be limited to 5 slides maximum and should be structured as: introduction, results (max. 3 figures, 1 figure per slide) and discussion. If you do not have any results from your study yet, just present the background, hypothesis and methods of your study.

Please pay extra attention to the visibility and readability of your presentation in general and the figures in particular. Bear in mind that it will be projected on a TV screen, so try to avoid a lot of text. Too much text will reduce the readability thereby making it too difficult for your audience to understand and follow your presentation. Try to use schemes instead of text to present your introduction and/or discussion and omit summarizing all methodological details. Instead, focus on the figures so that your audience can read and understand them from where they are seated in the room.

After the presentation, a short 5-10 minute discussion will follow which is focused on two subjects:
1) way of presenting based on the PowerPoint layout and presentation skills, and
2) data and project including potential problems or pitfalls. 
Additionally, you could ask for advice or simply get inspired with new stimulating ideas from the group.

In order to ensure an equal amount of time for all participants, you are kindly asked to keep this time restriction in mind when preparing your presentation. During the Masterclass, a moderator from the board of the Young Investigator Meeting will be present to control the time management.

Please upload your PowerPoint presentation (max 5 slides) using the link at the bottom of the page, before November 8th.

At the end of the day, the key-note speakers leading the various Masterclasses will select the best presentation which will be awarded with the NRS YIS Masterclass presentation prize of € 500,-.

Workshop - Data visualisation for researchers

Postdocs can choose to follow a masterclass supervised by one of the speakers as described above, or can participate in the workshop 'Data visualisation for researchers'. Clear communication of scientific findings is essential in academia. On top of the ‘classic’ text-heavy scientific papers, the importance of visual communication through tables, graphs, visual abstracts and infographics is more and more acknowledged. A well-designed data visualisation can greatly increase the communicative power of publications, (poster-) presentations and grant proposals.

In this workshop you will learn how to clearly communicate scientitic findings though visual means:

  • starting from a conceptual basis (“how does our brain process visual information?”), the design principles behind a good data visualisation will be explained
  • “exploratory” and “explanatory” data visualisations will be discussed: their differences and the roles they play in academia
  • the impact of design choices will be illustrated based on visualisation examples handed in by the masterclass’ participants

Note: this workshop is “tool-independent”: you will not be taught a specific data visualisation tool, nor do you need knowledge on any data visualisation tool prior to this workshop.

Short bio of the trainer Sara Maria Sprinkhuizen:
Sara got her PhD in physics at Utrecht University, after which she moved to Boston for a post-doc in MRI scanner physics. After 7 years she moved back to the Netherlands, working as a freelancer on data analysis and data visualisation projects. She currently works as a data visualiser for the Dutch Journal of Medicine (Nederlands Tijdschrift voor Geneeskunde) and data analyst & visualiser at the Màxima Medical Center in Eindhoven.

Refreshments will be served during these sessions.


Besides the NRS YIS Masterclass presentation prize, also the NRS SAB Best Paper Award will be awarded. The SAB Best Paper Award is presented every year to a young investigator who performed his/her research in a research institute or hospital in the Netherlands, or to a Dutch investigator who performed his/her research abroad. 


Prof. dr. Alvar Agustí, Respiratory Institute, Hospital Clinic, University of Barcelona, Spain

Prof. Alvar Agustí is currently Director of the Respiratory Institute at Hospital Clinic in Barcelona (www.hospitalclinic.org), and Professor of Medicine at the University of Barcelona. His main research interest relates to clinical and translational research in chronic airway diseases. He has published more than 500 papers in peer-reviewed journals (H-Index 105) and has over 40 contributions to books. He is regularly invited to speak at international conferences and symposia. He is a member of several professional societies, including the American Thoracic Society (where he has been associated editor of the Am. J. Respir. And Crit. Care Med.), and the European Respiratory Society (in which he has been a Member of its Executive Committee). He has a sit at the Royal Academy of Medicine of the Balearic Islands, he is an Honorary Fellow of the Royal College of Physicians of Edinburgh (FRCP), a Fellow of the European Respiratory Society (FERS), Honorary member of ERS, and current Chair of the Board of Directors of GOLD (www.goldcopd.org).

Main publications:


Prof. dr. Leo Koenderman, University Medical Centre Utrecht, the Netherlands

Leo Koenderman is professor at University Medical Center Utrecht. After completion of his PhD “Signal transduction in human granulocytes” in 1990, he became Head of laboratory Experimental Pulmonology in 1993 and professor in 2000. He supervised 46 PhD students that successfully obtained their degree. Prof. Koenderman is currently secretary of the Netherlands Inflammation Network. He gave >40 invited lectures at international congresses and symposia. H-factor: 55  (web of knowledge), Peer reviewed articles: 264 (medline), Citations : 11,904 (web of knowledge), 2 Patents (EU: WO2008/0/75962, US: US 8,460,883 B2).

Main publications:

  • van Staveren S, Ten Haaf T, Klöpping M, Hilvering B, Tinnevelt GH, de Ruiter K, Piacentini MF, Roelands B, Meeusen R, de Koning JJ, Jansen JJ, Vrisekoop N, Koenderman L. Multi-dimensional flow cytometry analysis reveals increasing changes in the systemic neutrophil compartment during seven consecutive days of endurance exercise. PLoS One. 2018 Oct 30;13(10):e0206175. doi: 10.1371/journal.pone.0206175
  • Hellebrekers P, Vrisekoop N, Koenderman L. Neutrophil phenotypes in health and disease. Eur J Clin Invest. 2018 Nov;48 Suppl 2:e12943. doi: 10.1111/eci.12943
  • Lord JM, Midwinter MJ, Chen YF, Belli A, Brohi K, Kovacs EJ, Koenderman L, Kubes P, Lilford RJ. The systemic immune response to trauma: an overview of pathophysiology and treatment. Lancet. 2014 Oct 18;384(9952):1455-65. doi: 10.1016/S0140-6736(14)60687-5.
  • Pillay J, Kamp VM, van Hoffen E, Visser T, Tak T, Lammers JW, Ulfman LH, Leenen LP, Pickkers P, Koenderman L A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1. J Clin Invest. 2012 Jan;122(1):327-36. doi: 10.1172/JCI57990

Prof. dr. Michel van den Heuvel, Radboud University Medical Centre in Nijmegen, The Netherlands

Michel van den Heuvel is professor at the Radboud University Medical Center Nijmegen. Michel is the head of the department Respiratory Diseases and is specialized in the thoracic oncology. Within the thoracic oncology field he has extensively published on topics related to chemoradiotherapy, immunotherapy and targeted therapy. He has experience in both clinical trials and translational research and is currently heading several nationale biomarker development and immunotherapy projects in lung cancer. Michel is member of the Section Oncology from the Dutch lung cancer society.

Prof. dr. Job van der Palen, Medisch Spectrum Twente and University of Twente, Enschede, the Netherlands

Professor Job van der Palen is a clinical epidemiologist who started his PhD in Medisch Spectrum Twente hospital in Enschede in 1993 on self-management in asthma. Following the successful completion of his PhD he has built a research line on self-management in respiratory diseases, mainly in COPD. This has resulted in various PhD projects such as the COPE I, II, and III studies, and the development and evaluation of the effect of smoking cessation interventions. Since 2009 he is also a part-time professor at the University of Twente.

  • JJ Klein, J van der Palen, SM Uil, GA Zielhuis, ER Seydel, CLA van Herwaarden. Benefit from the inclusion of self-treatment guidelines to a self-management programme for adults with asthma. Eur Respir J 2001; 17: 386-394
  • Monninkhof E, van der Valk PD, van der Palen J, van Herwaarden C, Zielhuis G. Effects of a comprehensive self-management programme in patients with chronic obstructive pulmonary disease. Eur Respir J 2003; 22: 815-20
  • Christenhusz LC, Prenger R, Pieterse ME, Seydel ER, van der Palen J. Cost-effectiveness of an Intensive Smoking Cessation Intervention for COPD Outpatients. Nicotine Tob Res. 2012;14(6):657-63
  • TW Effing, HAM Kerstjens, PD Van Der Valk, GA Zielhuis, J Van Der Palen. The (cost)-effectiveness of self-treatment of exacerbations on the severity of exacerbations in COPD patients: the COPE-II study. Thorax 2009; 64(11):956-62
  • Effing T, Zielhuis GA, Kerstjens HA, van der Valk PA, van der Palen J. Community based physiotherapeutic exercise in COPD self-management: A randomised controlled trial. Resp Med 2011;105(3):418-26
  • Zwerink M, van der Palen J, Kerstjens HA, van der Valp P, Brusse-Keizer M, Zielhuis G, Effing T. A community-based exercise programme in COPD self-management: Two years follow-up of the COPE-II study. Respir Med 2014;108(10):1481-90
  • Zwerink M, Kerstjens HA, van der Palen J, van der Valk PD, Brusse-Keizer M, Zielhuis G, et al. (Cost-)effectiveness of self-treatment of exacerbations in patients with COPD: 2 years follow-up of a RCT. Respirology 2016;21(3):497-503
  • Lenferink A, van der Palen J, van der Valk PDLPM, Cafarella P, van Veen A, Quinn S, Groothuis-Oudshoorn CGM, Burt MG, Young M, Frith PA, Effing TW. Exacerbation action plans for patients with COPD and comorbidities: a randomised controlled trial. Eur Respir J. 2019 Aug 14

If you have any questions, please contact the Young Investigator Board by sending an email to nrs-secr@outlook.com .

We hope to see you all November 15th.

The NRS Young Investigators Board,

Dr. Nienke Vrisekoop (chair), UMC Utrecht
Dr. Anke Lenferink (vice chair), University of Twente
Dr. Marieke Duiverman, UMC Groningen 
Dr. Bram van den Borst, Radboud UMC 
Dr. Susanne Vijverberg, UMC Amsterdam